New evidence unearthed by Dr Jack
Levenson, the dentist who has led the fight against amalgam fillings
in the UK, shows that dental fillings could be behind the burgeoning
of many 20th century conditions.
It is generally accepted that when a disease such as influenza
reaches 400 per 100,000, or 0.4 per cent of the population, it
is then considered to be of epidemic proportions. In January 1997,
the British Dental Association (BDA) issued a fact file on mercury,
stating: "About 3 per cent of the population are estimated to
"
Three per cent of the UK population alone would represent some
1.75 million people, of whom about one million would have mercury
Despite these potentially huge casualties, no action is taken
on mercury toxicity and, unlike BSE and AIDS, it has attracted
relatively little media attention. No public money has been allocated
Nevertheless, current research suggests that mercury vapour from
fillings may be one of the predominant underlying causes of a
broad spectrum of conditions, ranging from gum disease, migraine,
headaches, poor memory, depression, anxiety, mental lethargy,
chronic fatigue, growth, allergies such as eczema and asthma,
and sensitivity reactions to food and inhalants, to rheumatism,
arthritis, backache, kidney disease, Alzheimer's disease, Parkinson's
HORMONAL IMBALANCES
Some research has focused on particular problems among women exposed
to mercury. One study showed that such women experienced disturbances
in the menstrual cycle such as excessive blood flow, irregular
periods, premenstrual tension (PMS) and painful menstruation (Pediatr
Akush Ginekol, 1971; 33: 56 8). Another showed a higher than expected
incidence of spontaneous abortion and premature labour (cordon
A, "Pregnancy in Female Dentists A Mercury Hazard", presented
at the International Conference of Mercury Hazards in Dental Practice,
Glasgow, 1981) in women exposed to mercury compared with controls.
Their rate of failure of ovulation was also nearly double that
Tests were carried out at the University of Heidelberg on women
who had hormonal irregularities and amalgam fillings and who had
difficulty in conceiving. At the same time, blood samples were
investigated for levels of pesticide contamination. The women
tested showed higher levels of urine mercury when given a test
that measures the amount of mercury excreted through a chelating
The most common problem by far was mercury contamination, which
correlated with the number of amalgam fillings. After removing
the fillings, nutritional support and treatment of other environmental
contamination burdens, 70 per cent of the women became pregnant
without the aid of hormonal therapy (Gynakologie, 1992; 14: 593
602). Further tests carried out at the University of Heidelberg
involved 132 women with amalgam fillings who had abnormal hair
growth or hair loss. Nearly half 49 per cent of these women showed
significantly elevated mercury levels. After removal of their
fillings, the symptoms disappeared in 68 per cent of cases (Klin
But it is not only women who suffer infertility problems caused
by mercury. It has been estimated that about 50 per cent of infertility
problems are associated with defective male sperm motility (Pharmacol
Workers who are occupationally exposed to mercury vapour have
been found to have a significant reduction in fertility rate (Am
MERCURY AND THE HEART
Heart attacks were practically unknown in the nineteenth century
There is no full explanation for the substantial increase in heart
disease, but the suspect factors are mainly diet, stress, smoking
Increasing evidence points to amalgam fillings as one major contributory
A series of studies carried out at Washington University (Proc
Soc Exper Biol Med, 1965; 120: 805 8; Proc Soc Exper Biol Med,
1967; 124: 485 90; Am J Physiol, 1970; 219: 755 61; Am J Physiol,
1971; 220: 808 11) demonstrated that mercury causes hypertension
by contracting smooth muscle in arterial walls. Inorganic mercury
caused blood vessel constriction and subsequent hypertension within
minutes of exposure organic mercury did not. The work was subsequently
confirmed by researchers at Harvard Medical School (Am J Physiol,
In 1974, the National Institute of Health, part of the US Department
of Health, Education and Welfare, published a 333 page account
of research in the Soviet Union on the effects of chronic exposure
to mercury and its compounds (Cardiotoxic Effects of Mercury,
DHEW (NIH) Publication No 74 473, 1974, pp 109 34, 199 210). They
reported that mercury affected the function of the heart in a
variety of ways, including the ability of heart muscle to contract,
The Soviet researchers also found that mercury produced functional
changes in cardiac activity and in heart muscle, and that it accumulated
in heart muscle and valves. The damage was evident from ECG changes
and through histological studies. They found that heart function
was influenced by the effect of mercury on hormones from the pituitary
In 1983, work carried out at the medical school at Lodz in Poland
(Thromb Res, 1983; 30: 579 85) found that various mercury compounds
In 1990, Siblerud (SRI Total Environ, 1990; 99: 23 35) compared
subjects with and without amalgam. They found that those with
amalgam had significantly higher blood pressure, lower heart rate
and lower haemoglobin counts. They also had a greater incidence
of chest pains, tachycardia, anaemia and fatigue, and became tired
easily and awoke feeling tired. The researchers concluded that:
"The data suggest that inorganic mercury poisoning from dental
".
MERCURY AND THE IMMUNE SYSTEM
In 1984, David Eggleston, Associate Professor at the Department
of Restorative Dentistry, published a preliminary report which
demonstrated the ability of amalgam and nickel to affect the total
percentages of T cells (J Prost Dent, 1984; 51: 617 23) those
cells which help killer cells to recognise foreign invaders. Two
cases involving dental amalgam, and one involving nickel, were
presented. The results were similar in all cases. In one of Eggleston's
21 year old patients who had six amalgam fillings, 47 per cent
of lymphocytes were T lymphocytes with amalgam fillings. After
removal of these fillings, 73 per cent of lymphocytes were T lymphocytes
When four amalgam fillings were again placed in the patient, the
T lymphocyte count dropped to 55 per cent a decrease of 24.7 per
cent. When the patient's amalgam fillings were replaced with gold,
the T lymphocyte count rose from to 72 per cent an increase of
The most recent research (Int J Occup Med Tox, 1995; 4) involving
34 patients with CNS disorders indicated intoxication from dental
amalgam. Tests showed pathological findings in 88 per cent of
these patients, of whom 60 per cent showed an immune reaction
to mercuric chloride. These findings support the view that chronic
low level exposure to mercury can compromise or weaken the im
mune system and adversely affect the defence mechanisms of the
ME AND CHRONIC FATIGUE
Mercury may contribute to chronic fatigue conditions and, in some
cases, play a predominant role. Chronic fatigue is one of the
main presenting symptoms of mercury toxicity, and practitioners
expect the condition to improve when fillings are removed. Patients
who are severely ill, and often bedridden and test positive to
mercury find that symptoms improve to a varying degree when amalgam
fillings are removed, but are not cured unless mercury is the
In one instance, a 42 year old GP had been housebound for four
years with severe chronic fatigue syndrome (ME). She could only
leave home for short journeys using a wheelchair, and had great
difficulty in climbing stairs. She had 13 amalgam fillings and
tested positive to mercury on a lymphocyte response test. Besides
ME symptoms, she also complained of other symptoms such as burning
mouth, blurred vision, nausea, constant lowgrade diarrhoea, muscle
pain, depression, tension, irritability, poor memory, low blood
pressure, asthma, sinus pain, aching joints and allergies to a
The patient had all her amalgam fillings removed and, three months
later, reported that her physical and mental energy had improved
and that her nausea was completely cleared. She was also enjoying
her food for the first time in years. The day after her final
fillings were removed, her husband gave her some soup. She was
amazed that it was the same soup her husband had given her the
day before, which she had found tasteless. She also reported that
her muddle headedness and lack of concentration had improved,
and that she felt much more relaxed. Two years later, the patient
Whether mercury was the initial cause of her chronic fatigue is
a matter of conjecture. What this case illustrates is that even
though, in some cases, mercury may not be the predominant causative
BACTERIAL RESISTANCE TO ANTIBIOTICS
A survey of 356 patients who had not recently been exposed to
antibiotics showed a high prevalence of mercuryresistant bacteria.
They were also significantly more likely to concurrently have
resistance to two or more antibiotics (Antimicrob Agents Chemother,
These findings prompted a three university collaborative investigation
in primates (Antimicrob Agents Chemother, 1993; 37:825 34). This
showed that a large proportion of common oral and intestinal bacteria
became resistant to mercury two weeks after receiving amalgam
fillings. Nearly all the mercury resistant bacteria were resistant
to one or more antibiotics such as tetracycline, ampicillin, streptomycin
and erythromycin. As in the human study, the monkeys had not had
recent exposure to antibiotics, demonstrating that the bacteria
had become antibiotic resistant due to exposure to mercury from
In both studies, the proportion of mercury and antibiotic resistant
bacteria declined markedly during the two months after amalgam
These studies confirm earlier work carried out in Japan (Antimicrob
Agents Chemother, 1997; 11: 999 1003; Appl Environ Microbiol,
1977; 33: 975 6; Nature, 1977; 266: 165 7) which showed that the
bacterial resistance to antibiotics and mercury can be transferred
to other bacteria by strands of DNA. The mercury resistant bacteria
constantly recirculate the mercury as vapour exacerbating the
increase of antibiotic resistant bacteria. Thus, the situation
In a recent paper (Sci Prog, 1997; 80: 103 6), a team from the
Eastman Dental Institute pointed out: "It must be remembered that
oral streptococci are a major cause of infective endocarditis
with a high mortality". The general systemic consequences of the
inability of antibiotics to contain or eliminate these resistant
bacteria, commonly called 'superbugs', is an escalating and serious
Research has shown that mercury from dental amalgam fillings:
1. increases mercury resistant bacteria, resulting in the constant
2. increases antibiotic resistance in bacteria the superbugs with
3. that bacteria are capable, via DNA strands, of transferring
4. mercury in the body and antibiotic-resistant bacteria markedly
Dr Jack Levenson Dr Levenson is author of "Menace in the Mouth"
If you have a health condition, have undergone conventional medical
investigation to exclude life threatening and other diseases,
and have not responded to treatment, you should have an experienced
* Check your dental status (fillings, crowns, implants, dentures
* Carry out a test to measure each metallic filling for electrical
activity, which will indicate the amount of mercury vapour released
from fillings and the possible systemic effects of having a 'battery'
* Consider a provocation urine test. This uses the known mercury
chelator 2,3 dimercaptosuccinic acid (DMSA) to leech mercury out
of your system to be excreted in the urine. Urine is taken before
and after swallowing this chelator, and compared for mercury content.
This test is an indicator of mercury body burden and requires
* Have a blood test the metal specific memory T cell test (MSMT)
developed at the Chelsea & Westminster Hospital in London
(020 8746 8000) which determines your immunological reactions
to dental and associated metals, and measures lymphocyte response
Other laboratory tests include hair analysis and a sweat test
Other tests to give you an indication of amalgam toxicity include
electroacupuncture evaluation (where an EAV practitioner assesses
problems in the meridians which run across individual teeth),
kinesiology, faeces measurement, a complete blood count and various
* Get advice on an individualised programme of vitamin/ mineral
supplementation and detoxification programme, and start it two
* Consume a fresh, organic wholefood diet. Avoid foods which are
salty, sour or eaten at a high temperature, and snacks between
* Take antioxidants and free radical scanvengers to help bind
and excrete mercury, including a good multivitamin supplement
and extra selenium (50 200 micrograms), vitamin C powder, seaweed
and homoeopathic dental amalgam, a tried and tested way to remove
* Constipation, if present, must be treated, as mercury may be
* Take charcoal half an hour prior to treatment to mop up any
mercury vapour which has evaded other precautionary procedures
* Get tested for your reaction to composite (white) fillings by
sucking a sample of the proposed restorative material for two
hours, repeating the procedure two days later, then monitoring
* Find a dentist experienced in removing amalgam fillings and
discuss the protocol beforehand. He/she should be familiar with
removing them in a predetermined sequence depending on ammeter
After treatment
* Embark on an extensive detox programme for a number of months
with supplements, detox measures such as saunas and steam, and
* Consider taking a chelator such as DMSA to flush mercury out
The pituitary is the master gland of the body and exerts an influence
Tissues which normally contain only a small fraction of the total
mercury found in the human body may contain higher concentrations
of mercury than the largest organs the kidneys and brain. This
was shown in the pituitary and thyroid glands of mercury miners
who had retired some years before their death. Their glands contained
very high concentrations of mercury greater than the levels found
The reason for these high concentrations is not difficult to understand
as there is a direct lymphatic pathway from the gingiva of the
lower jaw to the thyroid, while the pituitary and thyroid are
both highly vascularised and have no protective barriers against
The kidney, the repository of waste in the body, is a target organ
for mercury. To test the effect of mercury on kidney function,
12 amalgam fillings were placed in the occlusal surfaces of six
adult female sheep. In addition, 12 glass ionomer fillings were
placed in two other sheep as controls (Am J Physiol, 1990; 258:
Kidney function, determined by glomerular filtration rate (insulin
clearance), was reduced by 50 per cent within 30 days. Urine potassium
levels increased a little while sodium levels showed a greater
increase. There was a reduction in albumin a water soluble protein
Low sodium levels in the blood stimulate the kidneys to release
renin, an enzyme that causes increased blood pressure. When sodium
and potassium are not present in their correct ratios, muscle
weakness, fatigue and heart irregularities are among the symptoms
Albumin is important for maintaining plasma volume. Changes in
albumin ratio adversely affect nutrient distribution to cells.
Human studies (Am J Physiol, 1990; 261: 1010 4) have demonstrated
an increase in urinary albumin 12 months after patients with amalgam
fillings had them removedsuggesting that the kidneys are able